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Beilstein J. Org. Chem. 2018, 14, 318–324, doi:10.3762/bjoc.14.20
Graphical Abstract
Scheme 1: Flow synthesis for the preparation of fused pyrimidinones 9–14 by rDA reaction. Solvent and conditi...
Figure 1: Schematic outline of the continuous-flow reactor.
Scheme 2: Synthesis of tricyclic ethanoquinazolin-4(3H)-one 15b; (i) MeCN, FR = 0.5 mL min−1, 220–250 °C; (ii...
Beilstein J. Org. Chem. 2013, 9, 1508–1516, doi:10.3762/bjoc.9.172
Figure 1: Examples of 1,2,3-triazoles with various biological activities.
Scheme 1: 1,3-Dipolar azide–alkyne cycloadditions.
Figure 2: Selected bioactive alicyclic β-amino acids.
Figure 3: Experimental setup for the CF reactions.
Scheme 2: Gramm-scale CF synthesis of triazole 22 under conditions B.